Treatment-Resistant Depression
Not everyone responds to the first treatment they try for depression. For some, symptoms persist even after trying multiple antidepressants or traditional therapies. This is known as treatment-resistant depression, and while it can feel frustrating or disheartening, there are effective options available, especially with support from a qualified mental health team.
At Mind Oasis Clinic, we provide personalised treatment for treatment-resistant depression, including access to TMS therapy, esketamine treatment and other psychiatrist-led care across Australia.
Understanding Treatment-Resistant Depression in Australia
Treatment-resistant depression in Australia refers to depression that hasn’t improved after trying at least two different antidepressants at adequate doses. It’s more common than many people think and can affect anyone, regardless of age or background.
Treatment resistance doesn’t mean there’s no hope. It simply means we need to take a different approach. That’s why treatment-resistant depression therapy often includes alternatives like transcranial magnetic stimulation (TMS) and esketamine, especially when standard options haven’t worked.
We offer support nationwide with psychiatrists in Canberra, Sydney, Melbourne, Brisbane and Adelaide.
Ready to Take the First Step?
Interested in exploring how you might benefit from
TMS or Esketamine Therapy for Treatment-Resistant Depression?
For Patients
Speak with our nurse to find out if these treatments might benefit you.
For GPs and Medical Professionals
Please email referrals to:
TMS Therapy for Treatment-Resistant Depression
TMS for treatment-resistant depression works by stimulating parts of the brain involved in mood regulation using magnetic pulses. It’s completely non-invasive and doesn’t require medication or sedation. Most people can drive themselves to and from their sessions and return to their normal routine straight away.
Compared to other treatments, transcranial magnetic stimulation therapy has been shown to work well for people with treatment-resistant depression, especially when medication hasn’t helped. Clinical research shows promising results in reducing symptoms and improving daily functioning.
Esketamine as a therapy for treatment-resistant depression
Esketamine is a prescription nasal spray that works differently from standard antidepressants. It targets glutamate receptors in the brain, which are involved in mood regulation. Unlike oral medications, esketamine can offer fast-acting relief, with some people noticing changes in a matter of hours or days.
Esketamine is used under medical supervision and is often combined with other therapies for longer-term results. It’s another option for people who haven’t responded well to traditional treatments and forms part of our broader treatment-resistant depression therapy options.
Finding Your Treatment Plan
We offer in-person transcranial magnetic stimulation treatment and Esketamine treatment in our Sydney clinic.
If you’re seeking a fresh approach to managing persistent symptoms, our personalised support makes it easier to find what works for you.
TMS Therapy for Treatment-Resistant Depression
TMS for treatment-resistant depression works by stimulating parts of the brain involved in mood regulation using magnetic pulses. It’s completely non-invasive and doesn’t require medication or sedation. Most people can drive themselves to and from their sessions and return to their normal routine straight away.
Compared to other treatments, transcranial magnetic stimulation therapy has been shown to work well for people with treatment-resistant depression, especially when medication hasn’t helped. Clinical research shows promising results in reducing symptoms and improving daily functioning.
Take the Next Step Toward Feeling Better
If you’ve been living with treatment-resistant depression and feel like nothing has worked, there are still options to explore. At Mind Oasis Clinic, we believe care should be personalised, compassionate, and based on what you need right now.
Our team offers expert therapy for treatment-resistant depression, including TMS therapy, esketamine treatment and access to mental health professionals across Australia.
Ready to Take the First Step?
Interested in exploring how you might benefit from
TMS or Esketamine Therapy for Treatment-Resistant Depression?
For Patients
Speak with our nurse to find out if these treatments might benefit you.
For GPs and Medical Professionals
Please email referrals to:
FAQs (Frequently Asked Questions) About Treatment-Resistant Depression
What does treatment-resistant depression mean?
Treatment-resistant depression means your symptoms haven’t improved after trying at least two different antidepressants. It doesn’t mean treatment won’t work—it just means a different approach may be needed, such as therapy, medication adjustments, or TMS therapy treatment.
Is TMS therapy effective for treatment-resistant depression?
Yes, TMS therapy for treatment-resistant depression has shown effectiveness in many people who haven’t responded to medications. It targets areas of the brain involved in mood and emotional processing and is considered a well-tolerated, low-risk option for treatment-resistant depression in Australia.
Can I still take antidepressants while undergoing TMS?
In most cases, yes. Your psychiatrist will review your current medications and treatment history before recommending a care plan. Sometimes, TMS works alongside medication, and in other cases, it’s used when other treatments haven’t helped.
What is esketamine and how does it help?
Esketamine is a fast-acting medication used as a nasal spray under medical supervision. It’s approved for use in treatment-resistant depression and may offer rapid relief from symptoms. It’s typically used alongside ongoing psychiatric care to monitor response and side effects.
Can I combine medication with TMS or esketamine?
In many cases, yes. TMS or esketamine can be used alongside your current medication plan. Your psychiatrist will assess what’s safe and appropriate based on your treatment history, diagnosis, and individual needs.
How long does it take to see results from TMS therapy?
Some people notice changes after a few sessions, while others may take a few weeks. A full course of TMS for treatment-resistant depression usually includes 25 to 35 sessions over several weeks. Your psychiatrist will monitor your progress throughout.
Is TMS available across Australia?
Yes. Mind Oasis provides transcranial magnetic stimulation therapy in Sydney, with referrals and assessments available for patients in Melbourne, Adelaide, Canberra, and Brisbane. Telehealth options are also available to ensure care remains accessible wherever you are. We also offer other services, including adult ADHD psychiatry.